The speaker notes Verve Therapeutics' collaboration with Beam Therapeutics to utilize base editing for treating hypercholesterolemia. This approach, if successful in clinical trials, could initially help high-risk patients and potentially be expanded to a wider population, addressing heart disease, which is the leading cause of death. This represents a significant long-term opportunity.
“a great example of this is the collaboration between verve therapeutics and beam therapeutics to use base editing to treat hypercholesterolemia by editing pcsk9”